L051823 DICER1 Virtual Symposium

May 18, 2023

Join us virtually for the 2023 DICER1 Symposium to discuss the latest findings in DICER1 and PPB clinical and laboratory research.

Target Audience

Healthcare professionals and researchers dedicated to improving outcomes for children and adults with DICER1-related conditions.

Learning Objectives

  • Identify DICER1-specific ACMG/AMP variant classification guidelines
  • Share clinical updates in DICER1-related cancers
  • Share updates in DICER1-related laboratory research
  • Provide opportunities for multidisciplinary discussion
     
Course summary
Available credit: 
  • 3.50 AMA PRA Category 1 Credit™
  • 3.50 Attendance
    • 3.50 Approved AMA PRA Category 1 Credit™
Course opens: 
04/19/2023
Course expires: 
06/21/2023
Event starts: 
05/18/2023 - 9:00am CDT
Event ends: 
05/18/2023 - 1:00pm CDT

*Agenda may be subject to change*

May 18, 2023

TimePresentation with speaker(s)

9:00AM – 9:10AM CST 

 Welcome 

9:10AM – 9:40AM CST

DICER1-specific modifications to the ACMG/AMP variant classification guidelines improve analysis of germline DICER1 variants with Jessica Hatton, MS, CGC  

9:40AM – 10:00AM CST

Clinical updates from the International PPB/DICER1 Registry with Kris Ann Schultz, MD 

10:00AM – 10:20AM CST

DICER1 the Israeli Experience with Tal Ben-Ami, MD & Orli Michaeli, MD 

10:20AM – 10:30AM CST

BREAK

10:30AM – 10:50AM CST

Development of liver-specific DICER1 syndrome model mouse with Shin-ichiro Ohno, PhD & Masahiko Kuroda, MD, PhD

10:50AM – 11:10AM CST

A genetically true model of DTPS as a platform for translational research with David Huntsman, MD 

11:10AM – 11:30AM CST

DICER1 deficiency in retinal disease with Bradley Gelfand, PhD 

11:30AM – 11:50PM CST

Cell and zebrafish approaches to studying DICER1 tumor predisposition syndrome with Mona Wu, PhD 
11:50AM - 12:10PM CSTGermline DICER1 loss promotes rhabdomyosarcoma via innate immune system with Randy Larsen, MS 

12:10PM – 12:30PM CST

Pineoblastoma: An imbalance between growth and differentiation with Kenneth Chen, MD 
12:30 PM – 1:00PM CSTQuestions and Roundtable Discussion 

 

DISCLOSURE STATEMENT:

It is our intent that any potential conflict should be identified openly so that the listeners may form their own judgments about the presentation with the full disclosure of the facts. It is not assumed any potential conflicts will have an adverse impact on these presentations. It remains for the audience to determine whether the speaker’s outside interest may reflect a possible bias, either the exposition or the conclusions presented.                                                                                                               

The following presenter(s) have disclosed they have a relevant financial relationship with an ineligible company whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients and have disclosed that a conflict of interest exists with the presentation. An explanation of how the conflict is being mitigated is listed below.

Bradley Gelfand, PhD has disclosed that he is co-founder of DiceRx which currently has no assets and all relevant financial relationships have been mitigated.

All other planning committee members and presenters have disclosed they have no relevant financial relationships with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients and have disclosed that no conflict of interest exists with the presentation/educational event.


FACULTY

Tal Ben-Ami, MD, Head of Pediatric Hematology-Oncology Unit, Kaplan Medical Center, Rehovot, Israel 

Kenneth Chen, MD, Center for Cancer and Blood Disorders, University of Texas- Southwestern

Bradley Gelfand, PhD, Associate Professor of Ophthalmology, University of Virginia 

Jessica Hatton, MS, CGC, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 

David Huntsman, MD, Director of Ovcare & Distinguished Scientist, Deputy Department Head, BC Cancer Agency Research Centre 

Masahiko Kuroda, MD, PhD, Department of Molecular Pathology, Tokyo Medical University, Tokyo, 160-8402, Japan 

Randy Larsen, MS, St. Jude Graduate School of Biomedical Science 

Orli Michaeli, MD, Division of Hematology/Oncology, Schneider Children’s Medical Center of Israel 

Shin-ichiro Ohno, PhD, Department of Molecular Pathology, Tokyo Medical University, Tokyo, 160-8402, Japan 

Kris Ann Schultz, MD, International PPB/DICER1 & OTST Registries, Cancer and Blood Disorders, Children’s Minnesota 

Mona Wu, PhD, Postdoctoral Research Fellow, Amatruda Lab, Division of Hematology-Oncology, Cancer and Blood Disease Institute, University of Southern California/ Children’s Hospital of Los Angeles 

Accreditation Statement:

In support of improving patient care, Children’s Minnesota is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Children’s Minnesota takes responsibility for the content, quality and scientific interest of its accredited continuing education events.

Credit Statement:

AMA

Children’s Minnesota designates this live activity for a maximum of 3.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent to their participation in the activity.

This program offers 3.5 contact hours of continuing education.  Most medical professional organizations accept AMA PRA Category 1 Credits™.  It is the individual’s responsibility to determine whether an education activity meets the continuing education requirements of their respective licensures and/or professional boards.  Go to your respective organization’s website for more detailed information regarding credit requirements.

Available Credit

  • 3.50 AMA PRA Category 1 Credit™
  • 3.50 Attendance
    • 3.50 Approved AMA PRA Category 1 Credit™
Please login or register to take this course.

Please click on the TAKE COURSE button to get started. You will navigate through the course pages by clicking the START COURSE or by accessing the content using the left-hand side navigation pane.

Children's Minnesota employees only

To add this event to your calendar, please follow these steps:

  1. Open your confirmation email from this course
  2. Click the add to calendar link (this will download the .ics file to your computer) 
  3. Open your Outlook calendar
  4. Select "Add calendar" from the left pane just above My Calendars
  5. Select "Upload from file" in the Add calendar window.
  6. Select Browse, go to your Downloads folder and select the .ics file.
  7. Select the Calendar you want the appointment to show up in, typically Calendar and then select Import.

Required Hardware/software

You will need a computer, iPad, or device with internet access to attend.